An Error-Control System Based on Majority-Logic Decoding

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryJoint Services Electronics Program / DAAB07-72-C-0259Rome Air Development Center / F30602-72-C-003

Experimental Unit for (31,16) Binary Code Using Majority-Logic Decoding

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryJoint Services Electronics Program / DAAB-07-72-C-0259Rome Air Development Center / F30602-72-C-003

Visualization of Frequent Itemsets with Nested Circular Layout and Bundling Algorithm

International audienceFrequent itemset mining is one of the major data mining issues. Once generated by algorithms, the itemsets can be automatically processed, for instance to extract association rules. They can also be explored with visual tools, in order to analyze the emerging patterns. Graphical itemsets representation is a convenient way to obtain an overview of the global interaction structure. However, when the complexity of the database increases, the network may become unreadable. In this paper, we propose to display itemsets on concentric circles, each one being organized to lower the intricacy of the graph through an optimization process. Thanks to a graph bundling algorithm, we finally obtain a compact representation of a large set of itemsets that is easier to exploit. Colors accumulation and interaction operators facilitate the exploration of the new bundle graph and to illustrate how much an itemset is supported by the data

Ultrahigh-Q Resonance in Bound States in the Continuum–Enabled Plasmonic Terahertz Metasurface

The study of optical resonators is of significant importance in terms of their ability to confine light in optical devices. A major drawback of optical resonators is the phenomenon of light emission due to their limited capacity for light confinement. Bound states in the continuum are gaining significant attention in the realization of optical devices due to their unique ability for reducing light scattering via interference mechanisms. This process can potentially suppress scattering, leading to improved optical performance. Using this concept, a metasurface having two elliptical silicon (Si) resonators nonidentically angled to create an outof-plane asymmetry is studied. Various parameters are optimized by employing a genetic algorithm (GA) to subsequently achieve a high-Q factor at terahertz frequencies. Herein, the device is fabricated using a novel method, and a thick high-index resonator is achieved. Terahertz measurements are carried out to validate the results. It is indicated in the experimental results that plasmons appear at the top surface of the metasurface and create strong sharp resonances that are sensitive to the external environment. Owing to strong field confinement ability, and high-Q factor, the metasurface is sensitive to its surrounding environment and can be essentially employed in terahertz sensing applications.Md Saiful Islam, Aditi Upadhyay, Rajour Tanyi Ako, Nicholas P. Lawrence, Jakeya Sultana, Abhishek Ranjan, Brian Wai-Him Ng, Nelson Tansu, Madhu Bhaskaran, Sharath Sriram, and Derek Abbot

The influence of R substituents in triphenylphosphinegold(I) carbonimidothioates, Ph 3PAu[SC(OR) = NPh] (R = Me, Et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways

The Ph3PAu[SC(OR) = NPh], R = Me (1), Et (2) and iPr (3), compounds are significantly cytotoxic to the HT-29 cancer cell line with1 being the most active. Based on human apoptosis PCR-array analysis, caspase activities, DNA fragmentation, cell apoptotic assays, intracellular reactive oxygen species (ROS) measurements and human topoisomerase I inhibition, induction of apoptosis is demonstrated and both the extrinsic and intrinsic pathways of apoptosis have been shown to occur. Compound1 activates the p73 gene, whereas each of2 and3 activates the p53 gene. An additional apoptotic mechanism is exhibited by2, that is, via the JNK/MAP pathway

Clustering Algorithms: Their Application to Gene Expression Data

Gene expression data hide vital information required to understand the biological process that takes place in a particular organism in relation to its environment. Deciphering the hidden patterns in gene expression data proffers a prodigious preference to strengthen the understanding of functional genomics. The complexity of biological networks and the volume of genes present increase the challenges of comprehending and interpretation of the resulting mass of data, which consists of millions of measurements; these data also inhibit vagueness, imprecision, and noise. Therefore, the use of clustering techniques is a first step toward addressing these challenges, which is essential in the data mining process to reveal natural structures and iden-tify interesting patterns in the underlying data. The clustering of gene expression data has been proven to be useful in making known the natural structure inherent in gene expression data, understanding gene functions, cellular processes, and subtypes of cells, mining useful information from noisy data, and understanding gene regulation. The other benefit of clustering gene expression data is the identification of homology, which is very important in vaccine design. This review examines the various clustering algorithms applicable to the gene expression data in order to discover and provide useful knowledge of the appropriate clustering technique that will guarantee stability and high degree of accuracy in its analysis procedure

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10-11 to 5.0 × 10-21). The sentinel blood pressure SNPs are enriched for association with DNA methylation at multiple nearby CpG sites, suggesting that, at some of the loci identified, DNA methylation may lie on the regulatory pathway linking sequence variation to blood pressure. The sentinel SNPs at the 12 new loci point to genes involved in vascular smooth muscle (IGFBP3, KCNK3, PDE3A and PRDM6) and renal (ARHGAP24, OSR1, SLC22A7 and TBX2) function. The new and known genetic variants predict increased left ventricular mass, circulating levels of NT-proBNP, and cardiovascular and all-cause mortality (P = 0.04 to 8.6 × 10-6). Our results provide new evidence for the role of DNA methylation in blood pressure regulation

Measurement of the cross section for isolated-photon plus jet production in pp collisions at √s=13 TeV using the ATLAS detector

The dynamics of isolated-photon production in association with a jet in proton–proton collisions at a centre-of-mass energy of 13 TeV are studied with the ATLAS detector at the LHC using a dataset with an integrated luminosity of 3.2 fb−1. Photons are required to have transverse energies above 125 GeV. Jets are identified using the anti- algorithm with radius parameter and required to have transverse momenta above 100 GeV. Measurements of isolated-photon plus jet cross sections are presented as functions of the leading-photon transverse energy, the leading-jet transverse momentum, the azimuthal angular separation between the photon and the jet, the photon–jet invariant mass and the scattering angle in the photon–jet centre-of-mass system. Tree-level plus parton-shower predictions from Sherpa and Pythia as well as next-to-leading-order QCD predictions from Jetphox and Sherpa are compared to the measurements

A search for resonances decaying into a Higgs boson and a new particle X in the XH → qqbb final state with the ATLAS detector

A search for heavy resonances decaying into a Higgs boson (H) and a new particle (X) is reported, utilizing 36.1 fb−1 of proton–proton collision data at collected during 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. The particle X is assumed to decay to a pair of light quarks, and the fully hadronic final state is analysed. The search considers the regime of high XH resonance masses, where the X and H bosons are both highly Lorentz-boosted and are each reconstructed using a single jet with large radius parameter. A two-dimensional phase space of XH mass versus X mass is scanned for evidence of a signal, over a range of XH resonance mass values between 1 TeV and 4 TeV, and for X particles with masses from 50 GeV to 1000 GeV. All search results are consistent with the expectations for the background due to Standard Model processes, and 95% CL upper limits are set, as a function of XH and X masses, on the production cross-section of the resonance